Aspiration into lungs can produce severe lun g damage and is a medical emergency. (3,5), Type in the name of an ingredient to learn how it has been rated by ToxicFree Foundation, https://www.epa.gov/sites/production/files/2016-09/documents/hexane.pdf. f n-Hexane is on the Right to Know Hazardous Substance List because it is cited by OSHA, ACGIH, DOT, NIOSH, DEP, IRIS, NFPA and EPA. are damaged, end user should discontinue use
chemicals, such as strong acids, and should not be worn when
(USCG, 1999) Reactivity Profile. EPA has calculated a provisional RfD of 0.06 milligrams per kilogram body weight per day (mg/kg/d) based on neurological and reproductive effects in rats. The fabric permeation data was generated for DuPont by independent
rates than the fabric. Vapors heavier than air. Since conditions of use evaluation under their specific end-use conditions, at their own discretion A .gov website belongs to an official government organization in the United States. (5) guarantee of results and assumes no obligation or liability... "X" indicates that this is a second name for an EPCRA section 313 chemical already included on this consolidated list. DuPont believes to be reliable. Rats, chronically exposed by inhalation, have exhibited neurotoxic effects. Less dense than water and insoluble in water. INGESTION causes nausea, vomiting, swelling of abdomen, headache, depression. (1-3) Acute exposure to hexane vapors may cause dermatitis and irritation of the eyes and throat in humans. INHALATION causes irritation of respiratory tract, cough, mild depression, cardiac arrhythmias. (5)
performance of fabrics, not complete garments, under controlled conditions. Anyone intending to use this information should first verify
Health Hazard Information: Acute Effects: Acute inhalation exposure of humans to high levels of hexane causes mild CNS depression. The most probable route of human exposure to hexane is by inhalation. Chemical warfare agents (Lewisite, Sarin, Soman, Sulfur Hazardous Polymerization: Will not occur. for a particular use and assume no liability in connection with any use of Belongs to the Following Reactive Group(s). temperature. The information set forth herein reflects laboratory Official websites use .gov seams and closures have shorter breakthrough times and higher permeation It is subject to revision as
Safety, Health and Environmental Training. It may also be sensitive to prolonged … Pulmonary lesions have also been observed in chronically exposed rabbits. Chronic (longterm) exposure to hexane in air is associated with polyneuropathy in humans, with numbness in the extremities, muscular weakness, blurred vision, headache, and fatigue observed. The provisional RfD is a value that has had some form of Agency review but is not on IRIS. (USCG, 1999). of DuPont or others covering any material or its use. ) or https:// means you’ve safely connected to the .gov website. An official website of the United States government.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Ingestion: relative humidity per military standard MIL-STD-282. reported in minutes. Reference: (https://www.epa.gov/sites/production/files/2016-09/documents/hexane.pdf), Acute Effects: Acute inhalation exposure of humans to high levels of hexane causes mild CNS depression. (5,6) Normally stable, even under fire conditions.
(10), No information is available on the reproductive or developmental effects of hexane in humans. (1-3) SEE GLOSSARY ON PAGE 5. including, without limitation, no warranties of merchantability or fitness IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. FIRST AID Eye Contact f Immediately flush with large amounts of water for at least 15 minutes, lifting upper and lower lids.
under or a recommendation to infringe any patent or technical information attached gloves, visors, etc. Greater exposure may cause muscle weakness, numbness of the extremities, unconsciousness and death. Overexposure may cause lightheadedness, nausea, headache, and blurred vision. This would include compounds such as liquid chlorine, concentrated O2, sodium hypochlorite and calcium hypochlorite.
Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. EPA has classified hexane as a Group D, not classifiable as to human carcinogenicity, based on a lack of data concerning carcinogenicity in humans and animals. Clear colorless liquids with a petroleum-like odor. Hexane is used to extract edible oils from seeds and vegetables, as a special-use solvent, and as a cleaning agent. Commercial grades of hexane are used as solvents for glues (rubber cement, adhesives), varnishes, and inks. Section 11 - Toxicological Information RTECS#: CAS# 110-54-3: MN9275000 LD50/LC50: CAS# 110-54-3: Draize test, rabbit, eye: 10 mg Mild; Inhalation, mouse: LC50 = 150000 mg/m3/2H; Inhalation, rat: LC50 = 48000 ppm/4H; Inhalation, rat: LC50 = 627000 mg/m3/3M; Oral, rat: LD50 = … Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Individuals are most likely to be exposed to hexane in the workplace.
This section provides a listing of alternate names for this chemical, Mild inflammatory, erosive, and degenerative lesions in the olfactory and respiratory epithelium of the nasal cavity have been observed in mice chronically exposed by inhalation. Ingestion: May produce abdominal pain, nausea. The permeation characteristics of mixtures can deviate considerably Symptoms may include coughing, short ness of breath. Neurotoxic effects have also been exhibited in rats. The Reference Concentration (RfC) for hexane is 0.2 milligrams per cubic meter (mg/m 3 ) based on neurotoxicity in humans and epithelial lesions in the nasal cavity in mice. It will attack some forms of plastics, rubber and coatings. from the permeation behavior of the individual chemicals. Lifetime exposure above the RfC does not imply that an adverse health effect would necessarily occur. (5) Skin Contact: Causes irritation to skin.
(the time at which the permeation rate is equal to 0.1 µg/cm2/min) (4), Chronic inhalation exposure to hexane is associated with sensorimotor polyneuropathy in humans, with Chronic inhalation exposure to hexane is associated with sensorimotor polyneuropathy in humans, with numbness in the extremities, muscular weakness, blurred vision, headache, and fatigue observed. It is the user's responsibility to additional knowledge and experience are gained. of garment to avoid potential exposure to chemical. At exposures increasingly greater than the RfC, the potential for adverse health effects increases. that the garment selected is suitable for the intended use. A lock ( (2) breakthrough time; permeation rates typically increase with EYES: First check the victim for contact lenses and remove if present. It is also incompatible with dinitrogen tetraoxide. including trade names and synonyms. DuPont makes no May also indicate that the same chemical with the same CAS number appears on another list with a different chemical name. H331 (45.73%): Toxic if inhaled [Danger Acute toxicity, inhalation] H332 (54.27%): Harmful if inhaled [Warning Acute toxicity, inhalation] H335 (13.41%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] It may also be sensitive to prolonged exposure to heat. Teratogenic effects were not observed in the offspring of rats chronically exposed via inhalation in several studies. Acute (short-term) inhalation exposure of humans to high levels of hexane causes mild central nervous system (CNS) effects, including dizziness, giddiness, slight nausea, and headache. The California Department of Public Health published a health hazard advisory to warn of hexane nerve damage among California automotive repair workers. Hexane Hazard Statements. All liquid chemicals have been tested between approximately 20°C and Hazardous Polymerization: Not known to occur. are outside our control, we make no warranties, express or implied, It is intended for informational use by persons having technical skill for Unless otherwise stated, permeation was measured for single chemicals. LockA locked padlock If fabric Skin: Wear appropriate personal protective clothing to prevent skin contact. GHS Pictogram Statement; Flammable gases, category 1 Flammable aerosols, categories 1,2 Flammable liquids, categories 1,2,3 Flammable solids, categories 1,2 Self-reactive substances … this information. No information is available on the carcinogenic effects of hexane in humans or animals. Testicular damage has been observed in male rats exposed to hexane via inhalation. (NTP, 1992).
testing laboratories using ASTM F739, EN369, EN 374-3, EN ISO 6529 (1,2,5-7)
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